Will Ferrell, Chad Smith join forces for all-star charity event with Jerry Seinfeld, Coldplay's Chris Martin and more
The Tonight Show Starring Jimmy Fallon/YouTube

Comedian and actor Will Ferrell and Red Hot Chili Peppers drummer Chad Smith have had a running joke about how much they look like each other. They famously did a "drum-off" dressed in identical clothes during a 2014 appearance on NBC's "The Tonight Show Starring Jimmy Fallon." Now, the two entertainers are teaming up for Will Ferrell’s Best Night of Your Life, an all-star charity benefit Cancer for College, with the show taking place Oct. 6 at the Greek Theatre in Los Angeles. Tickets can be purchased here.

Ferrell and Smith will be among the celebrities at the event that will have a mix of comedy and music. Comedians at the star-studded show include Jerry SeinfeldConan O’Brien, Samantha Bee, James Corden, Jimmy Kimmel, Zooey Deschanel, Kumail Nanjiani, Michelle Wolf, Jim Jefferies, Jerrod Carmichael and Brody Stevens.  Musicians who are set to perform in an include Coldplay lead singer Chris Martin, Brad Paisley, Pearl Jam guitarist Mike McCready, Guns N' Roses bassist Duff McKagan, Dave Matthews Band bassist Stefan Lessard and Red Hot Chili Peppers guitarist Josh Klinghoffer.

This is the type of event that should be on TV, streamed and/or released on home video. However, it's possible that Ferrell's comedy website Funny or Die, which is producing the event, will have highlight clips.

In 2016, Ferrell and Smith did a drum-off rematch, also during a Cancer for College charity event in Los Angeles, but that time, several famous drummers and joined in the drum-off such as Tommy Lee of Motley Crue, Mick Fleetwood of Fleetwood Mac, Stewart Copeland (formerly of The Police) and Taylor Hawkins of Foo Fighters. "Portlandia" comedian Fred Armisen also joined in on the drum-off.